UTROGESTAN / Progesterone / 100mg - Capsule 1's

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Nationwide (Philippines)

The standard daily dosage regimen is 200 to 300 mg of progesterone taken in one or two doses, i.e. 200 mg in the evening at bedtime and another 100 mg in the morning, if needed.

In the case of luteal phase defect (pre-menstrual syndrome, menstrual irregularity, pre-menopause, benign breast disease): the treatment is administered over 10 days per menstrual cycle, usually from cycle days 17 to 26 inclusive.

In the treatment of the menopause: given that stand-alone oestrogen therapy is not recommended, progesterone may be used as an adjuvant, to be given during the last two weeks of the treatment sequence, followed by a one-week suspension of all replacement therapy, during which withdrawal bleeding may be observed.

In the case of threatened abortion or in the prevention of LPD-related recurrent spontaneous abortions: the usual daily dosage is 200 mg to 400 mg progesterone, spread over two doses, to be taken up until gestation week 12.

In the case of threatened preterm delivery: 400 mg of progesterone every 6 to 8 hours, depending on the clinical results obtained during the acute phase, followed by a maintenance dose (e.g. 3 x 200 mg a day) to be taken up until gestational week 36.

• Progesterone